Did you know?

Lupus is one of America’s least recognized major diseases. While lupus is widespread, awareness and accurate knowledge about it is lacking. More than 90% of lupus sufferers are women, mostly young women between the ages of 15 to 44. Women of color are two to three times more at risk for lupus than Caucasians.

Lupus is very difficult to diagnose.

No single test can definitively determine whether a person has lupus — but several laboratory tests of blood and urine along with clinical assessment can help make a diagnosis.

What is Lupus?

Lupus is a chronic, complex and prevalent autoimmune disease that affects more than 1.5 million Americans. Lupus is difficult to diagnose because its symptoms come and go, mimic those of other diseases, and there is no single laboratory test that can definitively identify the illness. Early detection and treatment is the key to a better health outcome and can usually lessen the progression and severity of the disease. Mainly a Woman’s Disease

Serious Consequences

In lupus, the immune system, which is designed to protect against infection, creates antibodies that attack the body’s own tissues and organs — the kidneys, brain, heart, lungs, blood, skin, and joints. Lupus is a leading cause of premature cardiovascular disease, kidney disease and stroke among young women. Three Types of Lupus

Although “lupus” is used as a broad term, there are several different types of lupus: systemic lupus erythematosus (SLE), cutaneous affecting only the skin and drug-induced lupus triggered by a few medications.

Systemic lupus erythematosus (SLE) is the form of the disease that most people refer to when they say “lupus.” The word “systemic” means the disease can affect many parts of the body — including the kidneys, brain or central nervous system, blood and blood vessels, skin, lungs, heart and joints. Skin involvement occurs in up to 80% of patients.

Common Symptoms

Important information you need to know

Our Mission

Learn more about what inspires the 4 A Sisters


Learn how you can help.

Reason to Hope

Lupus is usually treated by a rheumatologist who specializes in treating diseases that affect the joints, muscles and bones. Specific manifestations of lupus, such as heart and kidney disease, may be treated by other types of physicians specializing in that field. Since lupus is highly individualized, and no two cases are exactly alike, the treatment also varies depending on the symptoms and needs of the patient. Anti-inflammatory drugs, anti-malarials, and steroids, such as prednisone, are used to treat lupus. Cytotoxic chemotherapies similar to those given in the treatment of cancer are also used to suppress the immune system in lupus patients.

While there are no known root causes or cure, the progress of recent discoveries and treatments in development is encouraging. In addition to funding studies paving the way for treatments to suppress the disease, the Lupus Research Institute initiated the Distinguished Innovators initiative to support research specifically aimed at finding the causes of lupus and driving towards prolonged drug-free remission — a cure.